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pc加拿大预算预测飞飞:李素云 副教授

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  李素云,中共党员,医学博士,pc加拿大预算预测飞飞医学部pc加拿大预算预测飞飞流行病与卫生统计学系,副教授,硕士生导师,山东省健康促进与健康学会身心健康促进专业委员会副主任委员、山东预防医学会卫生事业管理分会常务委员、山东预防医学会健康教育分会青年委员会委员。主要从事慢性非传染病流行病学、分子流行病学研究。目前主要研究方向为老年人认知功能的遗传及环境影响因素研究、老年人常见慢性非传染病的预防及控制。

  2012年毕业于重庆医科大学公共卫生与管理学院,获理学学士学位。2015-2016年,获国家留学基金委资助,赴美国布朗大学进行博士生联合培养,重点从事皮肤病流行病学研究。2017年6月毕业于山东大学pc加拿大预算预测飞飞流行病学系,硕博连读,获医学博士学位。同年12月,加入pc加拿大预算预测飞飞公共卫生与预防医学博士后流动站进行博士后研究,合作导师为张东峰教授。

  目前承担国家自然科学基金青年基金1项,山东省自然科学基金1项,中国博士后科学基金特别资助项目1项,中国博士后科学基金面上项目1项,青岛市博士后应用项目1项。已发表中英文论文40余篇,其中第一作者或通讯作者SCI论文17篇。主要承担本科生《医学统计学I》、《医学统计学II》,研究生《卫生统计学》、《医学多因素分析及软件应用》,及留学生《Medical  Statistics》等课程的教学工作。

一、主要研究方向

1. 慢性非传染病流行病学;

2. 皮肤病流行病学;

3. 分子流行病学

二、代表性科研成果(学术论文)

(1)  Wang, X.; Zhang, J.; Chen, C.; Lu, Z.; Zhang, D.; Li, S. The  Association between Physical Activity and Cognitive Function in the  Elderly in Rural Areas of Northern China. Front. Aging Neurosci. 2023,  15, 1168892. https://doi.org/10.3389/fnagi.2023.1168892. (共同通讯作者)

(2)  Zhang, J.; Wang, X.; Duan, H.; Chen, C.; Lu, Z.; Zhang, D.; Li, S. The  Association of Calcium Signaling Pathway Gene Variants, Bone Mineral  Density and Mild Cognitive Impairment in Elderly People. Genes 2023, 14  (4), 828. https://doi.org/10.3390/genes14040828. (通讯作者)

(3)  Chen, C.; Lu, Z.; Wang, X.; Zhang, J.; Zhang, D.; Li, S. The Chain  Mediating Role of C-Reactive Protein and Triglyceride-Glucose Index  between Lung Function and Cognitive Function in a Systemic Low-Grade  Inflammation State. J. Psychiatr. Res. 2022, S0022395622004940.  https://doi.org/10.1016/j.jpsychires.2022.09.004. (通讯作者)

(4)  Chen, C.; Lu, Z.; Wang, X.; Zhang, J.; Zhang, D.; Li, S.  Sugar-Sweetened Beverages Consumption Is Associated with Worse Cognitive  Functions in Older Adults: From the National Health and Nutrition  Examination Survey and Food Patterns Equivalents Database. Nutr.  Neurosci. 2022, 1–8. https://doi.org/10.1080/1028415X.2022.2115242. (通讯作者)

(5)  Lu, Z.; Chen, C.; Zhang, J.; Wang, X.; Zhang, D.; Li, S. The  Relationship between Alternative Healthy Diet Index and Cognitive  Function in the Older Adults: The Mediating Effect of Depressive  Symptoms. Nutrients 2022, 14 (14), 2856.  https://doi.org/10.3390/nu14142856. (通讯作者)

(6)  Chen, C.; Lu, Z.; Zhao, J.; Wang, X.; Zhang, J.; Zhang, D.; Li, S.  Combined Association of Depressive Symptoms and Sugar-Sweetened  Beverages Consumption with Low Cognitive Performance. J. Affect. Disord.  2022, 313, 15–20. https://doi.org/10.1016/j.jad.2022.06.071. (通讯作者)

(7)  Chen, C.; Lu, Z.; Zhang, D.; Li, S. The Mediation Role of the Risk of  Non-Alcoholic Fatty Liver Disease in Relationship between Lutein and  Zeaxanthin and Cognitive Functions among Older Adults in the United  States. Nutrients 2022, 14 (3), 578. https://doi.org/10.3390/nu14030578.  (通讯作者)

(8)  Li, S.; Sun, W.; Zhang, D. Association of Zinc, Iron, Copper, and  Selenium Intakes with Low Cognitive Performance in Older Adults: A  Cross-Sectional Study from National Health and Nutrition Examination  Survey (NHANES). J. Alzheimers Dis. 2019, 72 (4), 1145–1157.  https://doi.org/10.3233/JAD-190263.

(9)  Li, S.; Chen, M. L.; Drucker, A. M.; Cho, E.; Geng, H.; Qureshi, A. A.;  Li, W.-Q. Association of Caffeine Intake and Caffeinated Coffee  Consumption With Risk of Incident Rosacea in Women. JAMA Dermatol. 2018,  154 (12), 1394. https://doi.org/10.1001/jamadermatol.2018.3301.

(10)  Li, S.; Drucker, A. M.; Cho, E.; Qureshi, A. A.; Li, W.-Q. Reply to:  “Rosacea and Alcohol Intake.” J. Am. Acad. Dermatol. 2018, 78 (1), e27.  https://doi.org/10.1016/j.jaad.2017.09.026.

(11)  Li, S.; Wang, Q.; Pan, L.; Yang, X.; Li, H.; Jiang, F.; Zhang, N.; Han,  M.; Jia, C. The Association of Environmental, Individual Factors, and  Dopamine Pathway Gene Variation with Smoking Cessation. Psychol. Health  Med. 2017, 22 (8), 955–960.  https://doi.org/10.1080/13548506.2017.1300670.

(12)  Li, S.; Cho, E.; Drucker, A. M.; Qureshi, A. A.; Li, W.-Q. Cigarette  Smoking and Risk of Incident Rosacea in Women. Am. J. Epidemiol. 2017,  186 (1), 38–45. https://doi.org/10.1093/aje/kwx054.

(13)  Li, S.; Cho, E.; Drucker, A. M.; Qureshi, A. A.; Li, W.-Q. Alcohol  Intake and Risk of Rosacea in US Women. J. Am. Acad. Dermatol. 2017, 76  (6), 1061-1067.e2. https://doi.org/10.1016/j.jaad.2017.02.040.

(14)  Li, S.; Wang, Q.; Pan, L.; Li, H.; Yang, X.; Jiang, F.; Zhang, N.; Han,  M.; Jia, C. The Association of Dopamine Pathway Gene Score, Nicotine  Dependence and Smoking Cessation in a Rural Male Population of Shandong,  China: Dopamine Pathway Gene Score and Smoking Cessation. Am. J.  Addict. 2016, 25 (6), 493–498. https://doi.org/10.1111/ajad.12421.

(15)  Li, S.; Fang, L.; Zhou, Y.; Pan, L.; Yang, X.; Li, H.; Wang, Q.; Jiang,  F.; Zhang, N.; Han, M.; Jia, C. Mediation of Smoking Abstinence  Self-Efficacy on the Association of Nicotine Dependence with Smoking  Cessation. Eur. J. Public Health 2015, 25 (2), 200–204.  https://doi.org/10.1093/eurpub/cku183.

(16)  Li, S. ‐Y.; Qureshi, A. A.; Li, W. ‐Q. Basal Cell Carcinoma in Organ  Transplant Recipients. Br. J. Dermatol. 2016, 174 (1), 16–17.  https://doi.org/10.1111/bjd.14260.

(17)  Li, S.; Li, W. Oral Nicorandil May Induce Skin Ulcerations. Br. J.  Dermatol. 2015, 173 (2), 328–329. https://doi.org/10.1111/bjd.13936.

(18)  Sun, W.; Li, S.; Chen, C.; Lu, Z.; Zhang, D. Dietary Fiber Intake Is  Positively Related with Cognitive Function in US Older Adults. J. Funct.  Foods 2022, 90, 104986. https://doi.org/10.1016/j.jff.2022.104986.

(19)  Li, Y.; Zhang, C.; Li, S.; Zhang, D. Association between Dietary  Protein Intake and the Risk of Depressive Symptoms in Adults. Br. J.  Nutr. 2020, 123 (11), 1290–1301.  https://doi.org/10.1017/S0007114520000562.

(20)  Wu, Y.; Li, S.; Wang, W.; Zhang, D. Associations of Dietary Vitamin B1,  Vitamin B2, Niacin, Vitamin B6, Vitamin B12 and Folate Equivalent  Intakes with Metabolic Syndrome. Int. J. Food Sci. Nutr. 2020, 71 (6),  738–749. https://doi.org/10.1080/09637486.2020.1719390.

(21)  Wang, T.; Sun, S.; Li, S.; Sun, Y.; Sun, Y.; Zhang, D.; Wu, Y. Alcohol  Consumption and Functional Limitations in Older Men: Does Muscle  Strength Mediate Them? J. Am. Geriatr. Soc. 2019, 67 (11), 2331–2337.  https://doi.org/10.1111/jgs.16082.

(22)  Wang, T.; Feng, W.; Li, S.; Tan, Q.; Zhang, D.; Wu, Y. Impact of  Obesity and Physical Inactivity on the Long-Term Change in Grip Strength  among Middle-Aged and Older European Adults. J. Epidemiol. Community  Health 2019, 73 (7), 619–624. https://doi.org/10.1136/jech-2018-211601.

(23)  Duan, W.; Li, S.; Meng, X.; Sun, Y.; Jia, C. Smoking and Survival of  Breast Cancer Patients: A Meta-Analysis of Cohort Studies. The Breast  2017, 33, 117–124. https://doi.org/10.1016/j.breast.2017.03.012.

(24)  Li, H.; Li, S.; Wang, Q.; Jia, C. Associations of Cytochrome P450  Oxidoreductase Genetic Polymorphisms with Smoking Cessation in a Chinese  Population. Hum. Genet. 2016, 135 (12), 1389–1397.  https://doi.org/10.1007/s00439-016-1728-9.

(25)  Yang, X.; Li, S.; Pan, L.; Wang, Q.; Li, H.; Han, M.; Zhang, N.; Jiang,  F.; Jia, C. Assessment of Successful Smoking Cessation by Psychological  Factors Using the Bayesian Network Approach. Psychol. Health Med. 2016,  21 (5), 652–661. https://doi.org/10.1080/13548506.2015.1073337.

(26)  Wang, Q.; Li, S.; Pan, L.; Li, H.; Yang, X.; Jiang, F.; Zhang, N.; Han,  M.; Jia, C. Association between Variants in Nicotinic Acetylcholine  Receptor Genes and Smoking Cessation in a Chinese Rural Population.  2016, 4.

(27)  Li, H.; Li, S.; Wang, Q.; Pan, L.; Jiang, F.; Yang, X.; Zhang, N.; Han,  M.; Jia, C. Association of 5-HTTLPR Polymorphism with Smoking  Behaviors: A Meta-Analysis. Physiol. Behav. 2015, 152, 32–40.  https://doi.org/10.1016/j.physbeh.2015.09.006.

(28)  Jiang, F.; Li, S.; Jia, C. Smoking and the Risk of Systemic Lupus  Erythematosus: An Updated Systematic Review and Cumulative  Meta-Analysis. Clin. Rheumatol. 2015, 34 (11), 1885–1892.  https://doi.org/10.1007/s10067-015-3008-9.

(29)  Jiang, F.; Li, S.; Pan, L.; Jia, C. Association of the G1057D  Polymorphism in Insulin Receptor Substrate 2 Gene with Type 2 Diabetes  Mellitus: A Meta-Analysis. J. Diabetes Complications 2015, 29 (5),  731–736. https://doi.org/10.1016/j.jdiacomp.2015.04.017.

(30)  Jiang, F.; Li, S.; Pan, L.; Zhang, N.; Jia, C. Association of Anxiety  Disorders with the Risk of Smoking Behaviors: A Meta-Analysis of  Prospective Observational Studies. Drug Alcohol Depend. 2014, 145,  69–76. https://doi.org/10.1016/j.drugalcdep.2014.10.022.

(31)  Yang, X.; Chen, H.; Li, S.; Pan, L.; Jia, C. Association of Sleep  Duration with the Morbidity and Mortality of Coronary Artery Disease: A  Meta-Analysis of Prospective Studies. Heart Lung Circ. 2015, 24 (12),  1180–1190. https://doi.org/10.1016/j.hlc.2015.08.005.

(32)  Yang, X.; Chen, H.; Li, S.; Wang, Q.; Pan, L.; Jia, C. Association  between Monoamine Oxidase Gene Polymorphisms and Smoking Behavior: A  Meta-Analysis. Drug Alcohol Depend. 2015, 153, 350–354.  https://doi.org/10.1016/j.drugalcdep.2015.05.024.

(33)  Pan, L.; Yang, X.; Li, S.; Jia, C. Association of CYP2A6 Gene  Polymorphisms with Cigarette Consumption: A Meta-Analysis. Drug Alcohol  Depend. 2015, 149, 268–271.  https://doi.org/10.1016/j.drugalcdep.2015.01.032.

(34)  Li, H.; Zhou, Y.; Li, S.; Wang, Q.; Pan, L.; Yang, X.; Zhang, N.;  Jiang, F.; Han, M.; Jia, C. The Relationship between Nicotine Dependence  and Age among Current Smokers. Iran J Public Health 2015, 44, 6.

(35) 杨孝荣, 李素云, 潘璐璐, 李慧杰, 姜帆, 张楠, 韩明奎, 贾崇奇,农村男性吸烟者社会支持与戒烟成功关系的研究.中华流行病学杂志, 2015. 36(12): 1361-1364.

(36) 潘璐璐, 李素云, 周云平, 王强, 杨孝荣, 李慧杰, 姜帆, 张楠, 韩明奎, 贾崇奇,吸烟归因遗传认知与戒烟成功关系.中国公共卫生, 2015. 31(2): 202-205.

(37)潘璐璐, 李素云, 周云平,杨孝荣, 贾崇奇, 细胞色素P450 2A6基因多态性和吸烟行为关联的Meta分析.中华预防医学杂志, 2015. 49(2):172-177.

(38) 张楠, 李素云, 潘璐璐, 王强, 杨孝荣, 李慧杰, 姜帆, 韩明奎, 贾崇奇, 拒烟自我效能与年龄关系的研究.中华流行病学杂志, 2015. 36(5): 426-429.

(39) 姜帆, 李素云, 潘璐璐, 王强, 杨孝荣, 张楠, 李慧杰, 韩明奎, 贾崇奇, 拒烟自我效能在吸烟:θ现越溲坛晒τ跋斓闹薪樾вΨ治.中华流行病学杂志, 2015. 36(10): 1081-1084.

(40) 韩明奎, 周云平, 李素云, 潘璐璐, 杨孝荣, 李慧杰, 姜帆, 张楠, 贾崇奇, 吸烟原因与戒烟成功关系的优势分析.中华流行病学杂志, 2014(10):1083-1086.

三、主要科研项目

1. Wnt信号通路基因变异及代谢产物对老年人认知功能减退的预测研究,国家自然科学基金青年项目,24万,2021.1-2023.12,主持

2. 基于多组学技术的老年人认知功能减退的预测研究,中国博士后基金特别资助,18万,2019.6-2021.12,主持

3. 钙离子信号通路基因遗传变异与老年人认知功能的关联,中国博士后基金面上项目一等资助,8万元,2018.7-2020.12,主持

4. 钙离子信号通路基因遗传变异及环境因素与老年人认知功能的关联,青岛市博士后应用项目,5万元,2019.1-2020.12,主持

5. 基于表型不一致同卵双生子DNA甲基化与老年人认知功能的关系研究,国家自然科学基金,应急项目,15万元,2018.1-2018.12,参与

6. 基于网络生物学技术探讨尼古丁依赖关键基因变异对戒烟成功的影响,国家自然科学基金,面上项目,60万,2013.1-2016.12,参与

四、学术会议

1.The  75th Annual Meeting of Society for Investigative Dermatology (SID),  Scottsdale, Arizona (2016.5.10 - 2016.5.14).” Cigarette smoking and risk  of incident rosacea in women: A prospective study”. (Oral presentation)

2.第七届中国流行病学学术年会,江苏南京,2014年10月;

3. 第四届全国功能基因组学高峰论坛,北京顺义,2017年10月;

4. 山东预防医学会流行病学分会第六次会员代表大会暨六届一次学术会议,山东德州,2017年11月;

5. 山东预防医学会健康教育分会第四次会员代表大会暨学术交流会,山东青岛,2017年11月(大会交流);

6. 山东预防医学会慢性非传染性疾病预防与控制分会2017年学术年会暨慢病防控技能研讨会,山东济南,2017年12月;

五、主要荣誉称号及奖励

1. pc加拿大预算预测飞飞医学部第十二届中青年教师教学大奖赛普通话组三等奖,2020年12月

2. 2019年pc加拿大预算预测飞飞医学部春季学期MBBS留学生教学大奖赛二等奖,2019年6月

3. pc加拿大预算预测飞飞医学部第六届青年教师英文授课大赛优秀奖,2017年12月

4. 山东省优秀毕业生(博士),2017年3月.

5. 山东大学优秀毕业生(博士),2017年3月.

6. 重庆市优秀毕业生(本科),2012年7月.

六、联系方式

办公电话:0532-82991712;E-mail:suyunli@qdu.edu.cn







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